Comparison of the induction profile for drug disposition proteins by typical nuclear receptor activators in human hepatic and intestinal cells. [electronic resource]
Producer: 20080514Description: 805-19 p. digitalISSN:- 0007-1188
- ATP Binding Cassette Transporter, Subfamily B
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- biosynthesis
- ATP-Binding Cassette Transporters -- biosynthesis
- Aryl Hydrocarbon Hydroxylases -- biosynthesis
- Caco-2 Cells
- Cell Culture Techniques
- Cells, Cultured
- Chenodeoxycholic Acid -- pharmacology
- Constitutive Androstane Receptor
- Cytochrome P-450 CYP2B6
- Cytochrome P-450 CYP3A -- biosynthesis
- Cytochrome P-450 Enzyme System -- biosynthesis
- DNA-Binding Proteins -- agonists
- Dexamethasone -- pharmacology
- Dose-Response Relationship, Drug
- Enzyme Induction
- Epithelial Cells -- drug effects
- Hepatocytes -- drug effects
- Humans
- Intestinal Mucosa -- drug effects
- Membrane Transport Proteins -- biosynthesis
- Multidrug Resistance-Associated Protein 2
- Multidrug Resistance-Associated Proteins -- biosynthesis
- Oxidoreductases, N-Demethylating -- biosynthesis
- Phenobarbital -- pharmacology
- Pregnane X Receptor
- Pregnenolone Carbonitrile -- pharmacology
- RNA, Messenger -- biosynthesis
- Receptors, Cytoplasmic and Nuclear -- agonists
- Receptors, Steroid -- agonists
- Research Design
- Rifampin -- pharmacology
- Transcription Factors -- agonists
- Up-Regulation
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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