Normal view MARC view ISBD view

Martin, P

Comparison of the induction profile for drug disposition proteins by typical nuclear receptor activators in human hepatic and intestinal cells. [electronic resource] - British journal of pharmacology Feb 2008 - 805-19 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

ISSN: 0007-1188

Standard No.: 10.1038/sj.bjp.0707601 doi

Subjects--Topical Terms:
ATP Binding Cassette Transporter, Subfamily B
ATP Binding Cassette Transporter, Subfamily B, Member 1--biosynthesis
ATP-Binding Cassette Transporters--biosynthesis
Aryl Hydrocarbon Hydroxylases--biosynthesis
Caco-2 Cells
Cell Culture Techniques
Cells, Cultured
Chenodeoxycholic Acid--pharmacology
Constitutive Androstane Receptor
Cytochrome P-450 CYP2B6
Cytochrome P-450 CYP3A--biosynthesis
Cytochrome P-450 Enzyme System--biosynthesis
DNA-Binding Proteins--agonists
Dexamethasone--pharmacology
Dose-Response Relationship, Drug
Enzyme Induction
Epithelial Cells--drug effects
Hepatocytes--drug effects
Humans
Intestinal Mucosa--drug effects
Membrane Transport Proteins--biosynthesis
Multidrug Resistance-Associated Protein 2
Multidrug Resistance-Associated Proteins--biosynthesis
Oxidoreductases, N-Demethylating--biosynthesis
Phenobarbital--pharmacology
Pregnane X Receptor
Pregnenolone Carbonitrile--pharmacology
RNA, Messenger--biosynthesis
Receptors, Cytoplasmic and Nuclear--agonists
Receptors, Steroid--agonists
Research Design
Rifampin--pharmacology
Transcription Factors--agonists
Up-Regulation