Effects of KP-496, a novel dual antagonist at the cysteinyl leukotriene receptor 1 and the thromboxane A(2) receptor, on airway obstruction in guinea pigs. [electronic resource]
Producer: 20080514Description: 669-75 p. digitalISSN:- 0007-1188
- 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid
- Acetates -- pharmacology
- Administration, Inhalation
- Administration, Oral
- Airway Obstruction -- chemically induced
- Animals
- Anti-Asthmatic Agents -- administration & dosage
- Benzoates -- administration & dosage
- Benzoquinones -- pharmacology
- Bronchoconstriction -- drug effects
- Cyclopropanes
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Drug Therapy, Combination
- Guinea Pigs
- Heptanoic Acids -- pharmacology
- Leukotriene Antagonists -- administration & dosage
- Leukotriene D4
- Lung -- drug effects
- Male
- Membrane Proteins -- antagonists & inhibitors
- Ovalbumin
- Prostaglandin Antagonists -- administration & dosage
- Quinolines -- pharmacology
- Receptors, Leukotriene -- metabolism
- Receptors, Thromboxane A2, Prostaglandin H2 -- antagonists & inhibitors
- Respiratory Hypersensitivity -- immunology
- Sulfides
- Thiazoles -- administration & dosage
- Time Factors
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Publication Type: Comparative Study; Journal Article
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