Effects of the NMDA receptor antagonist memantine on the expression and development of acute opiate dependence as assessed by withdrawal-potentiated startle and hyperalgesia. [electronic resource]
Producer: 20080814Description: 649-60 p. digitalISSN:- 0033-3158
- Analgesics, Opioid -- adverse effects
- Animals
- Hyperalgesia -- physiopathology
- Male
- Memantine -- therapeutic use
- Morphine -- adverse effects
- Morphine Dependence -- physiopathology
- Naloxone -- administration & dosage
- Narcotic Antagonists -- administration & dosage
- Rats
- Rats, Sprague-Dawley
- Receptors, N-Methyl-D-Aspartate -- antagonists & inhibitors
- Reflex, Startle -- drug effects
- Substance Withdrawal Syndrome -- drug therapy
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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