Effects of the NMDA receptor antagonist memantine on the expression and development of acute opiate dependence as assessed by withdrawal-potentiated startle and hyperalgesia.
Harris, Andrew C
Effects of the NMDA receptor antagonist memantine on the expression and development of acute opiate dependence as assessed by withdrawal-potentiated startle and hyperalgesia. [electronic resource] - Psychopharmacology Mar 2008 - 649-60 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
0033-3158
10.1007/s00213-007-0998-2 doi
Analgesics, Opioid--adverse effects
Animals
Hyperalgesia--physiopathology
Male
Memantine--therapeutic use
Morphine--adverse effects
Morphine Dependence--physiopathology
Naloxone--administration & dosage
Narcotic Antagonists--administration & dosage
Rats
Rats, Sprague-Dawley
Receptors, N-Methyl-D-Aspartate--antagonists & inhibitors
Reflex, Startle--drug effects
Substance Withdrawal Syndrome--drug therapy
Effects of the NMDA receptor antagonist memantine on the expression and development of acute opiate dependence as assessed by withdrawal-potentiated startle and hyperalgesia. [electronic resource] - Psychopharmacology Mar 2008 - 649-60 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
0033-3158
10.1007/s00213-007-0998-2 doi
Analgesics, Opioid--adverse effects
Animals
Hyperalgesia--physiopathology
Male
Memantine--therapeutic use
Morphine--adverse effects
Morphine Dependence--physiopathology
Naloxone--administration & dosage
Narcotic Antagonists--administration & dosage
Rats
Rats, Sprague-Dawley
Receptors, N-Methyl-D-Aspartate--antagonists & inhibitors
Reflex, Startle--drug effects
Substance Withdrawal Syndrome--drug therapy