HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein. [electronic resource]
Producer: 20080416Description: 23-35 p. digitalISSN:- 1934-6069
- Animals
- Apoptosis Regulatory Proteins -- genetics
- Autophagy -- physiology
- Beclin-1
- Cell Line
- Cerebral Cortex -- cytology
- Humans
- Membrane Proteins -- genetics
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Neurons -- metabolism
- Phagosomes -- metabolism
- Protein Structure, Tertiary
- Saccharomyces cerevisiae -- genetics
- Survival Rate
- Two-Hybrid System Techniques
- Viral Proteins -- genetics
- eIF-2 Kinase -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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