HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein.

Orvedahl, Anthony

HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein. [electronic resource] - Cell host & microbe Mar 2007 - 23-35 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1934-6069

10.1016/j.chom.2006.12.001 doi


Animals
Apoptosis Regulatory Proteins--genetics
Autophagy--physiology
Beclin-1
Cell Line
Cerebral Cortex--cytology
Humans
Membrane Proteins--genetics
Mice
Mice, Inbred C57BL
Mice, Knockout
Neurons--metabolism
Phagosomes--metabolism
Protein Structure, Tertiary
Saccharomyces cerevisiae--genetics
Survival Rate
Two-Hybrid System Techniques
Viral Proteins--genetics
eIF-2 Kinase--genetics