Intrathecal delivery of hepatocyte growth factor from amyotrophic lateral sclerosis onset suppresses disease progression in rat amyotrophic lateral sclerosis model. [electronic resource]
Producer: 20071213Description: 1037-44 p. digitalISSN:- 0022-3069
- Amyotrophic Lateral Sclerosis -- drug therapy
- Animals
- Animals, Genetically Modified
- Blotting, Western
- Caspases -- drug effects
- Disease Models, Animal
- Disease Progression
- Enzyme-Linked Immunosorbent Assay
- Excitatory Amino Acid Transporter 2 -- drug effects
- Hepatocyte Growth Factor -- administration & dosage
- Humans
- Immunohistochemistry
- Infusion Pumps, Implantable
- Injections, Spinal
- Motor Neurons -- drug effects
- Nerve Degeneration -- drug therapy
- Proto-Oncogene Proteins c-met -- metabolism
- RNA, Messenger -- analysis
- Rats
- Reverse Transcriptase Polymerase Chain Reaction
- Spinal Cord -- drug effects
- X-Linked Inhibitor of Apoptosis Protein -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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