Cholesterol modulates cellular TGF-beta responsiveness by altering TGF-beta binding to TGF-beta receptors. [electronic resource]
Producer: 20080219Description: 223-33 p. digitalISSN:- 1097-4652
- Animals
- Apolipoproteins E -- deficiency
- CHO Cells
- Caveolae -- drug effects
- Cell Line
- Centrifugation, Density Gradient
- Cholesterol -- pharmacology
- Cricetinae
- Cricetulus
- Diet
- Endothelium, Vascular -- drug effects
- Female
- Iodine Radioisotopes
- Lipoproteins -- pharmacology
- Lovastatin -- pharmacology
- Membrane Microdomains -- drug effects
- Phosphorylation -- drug effects
- Protein Binding -- drug effects
- Protein Serine-Threonine Kinases -- metabolism
- Receptor, Transforming Growth Factor-beta Type I
- Receptor, Transforming Growth Factor-beta Type II
- Receptors, Transforming Growth Factor beta -- metabolism
- Smad2 Protein -- metabolism
- Time Factors
- Transforming Growth Factor beta -- pharmacology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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