Cholesterol modulates cellular TGF-beta responsiveness by altering TGF-beta binding to TGF-beta receptors.

Chen, Chun-Lin

Cholesterol modulates cellular TGF-beta responsiveness by altering TGF-beta binding to TGF-beta receptors. [electronic resource] - Journal of cellular physiology Apr 2008 - 223-33 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1097-4652

10.1002/jcp.21303 doi


Animals
Apolipoproteins E--deficiency
CHO Cells
Caveolae--drug effects
Cell Line
Centrifugation, Density Gradient
Cholesterol--pharmacology
Cricetinae
Cricetulus
Diet
Endothelium, Vascular--drug effects
Female
Iodine Radioisotopes
Lipoproteins--pharmacology
Lovastatin--pharmacology
Membrane Microdomains--drug effects
Phosphorylation--drug effects
Protein Binding--drug effects
Protein Serine-Threonine Kinases--metabolism
Receptor, Transforming Growth Factor-beta Type I
Receptor, Transforming Growth Factor-beta Type II
Receptors, Transforming Growth Factor beta--metabolism
Smad2 Protein--metabolism
Time Factors
Transforming Growth Factor beta--pharmacology