Pretreatment with the protegrin IB-367 affects Gram-positive biofilm and enhances the therapeutic efficacy of linezolid in animal models of central venous catheter infection. [electronic resource]
Producer: 20080211Description: 463-8 p. digitalISSN:- 0148-6071
- Acetamides -- pharmacology
- Animals
- Anti-Infective Agents -- pharmacology
- Antimicrobial Cationic Peptides
- Biofilms -- drug effects
- Catheterization, Central Venous -- adverse effects
- Colony Count, Microbial
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Enterococcus faecalis -- drug effects
- Gram-Positive Bacterial Infections -- prevention & control
- Linezolid
- Male
- Microbial Sensitivity Tests
- Oxazolidinones -- pharmacology
- Peptides -- pharmacology
- Random Allocation
- Rats
- Rats, Wistar
- Staphylococcal Infections -- prevention & control
- Staphylococcus aureus -- drug effects
- Treatment Outcome
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Publication Type: Journal Article
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