Pretreatment with the protegrin IB-367 affects Gram-positive biofilm and enhances the therapeutic efficacy of linezolid in animal models of central venous catheter infection.

Ghiselli, Roberto

Pretreatment with the protegrin IB-367 affects Gram-positive biofilm and enhances the therapeutic efficacy of linezolid in animal models of central venous catheter infection. [electronic resource] - JPEN. Journal of parenteral and enteral nutrition - 463-8 p. digital

Publication Type: Journal Article

0148-6071

10.1177/0148607107031006463 doi


Acetamides--pharmacology
Animals
Anti-Infective Agents--pharmacology
Antimicrobial Cationic Peptides
Biofilms--drug effects
Catheterization, Central Venous--adverse effects
Colony Count, Microbial
Disease Models, Animal
Dose-Response Relationship, Drug
Enterococcus faecalis--drug effects
Gram-Positive Bacterial Infections--prevention & control
Linezolid
Male
Microbial Sensitivity Tests
Oxazolidinones--pharmacology
Peptides--pharmacology
Random Allocation
Rats
Rats, Wistar
Staphylococcal Infections--prevention & control
Staphylococcus aureus--drug effects
Treatment Outcome