A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways. [electronic resource]
Producer: 20080204Description: 35279-92 p. digitalISSN:- 0021-9258
- Adipose Tissue -- metabolism
- Animals
- Bone Marrow Cells -- metabolism
- CD11b Antigen -- biosynthesis
- CD11c Antigen -- biosynthesis
- Fatty Acids, Nonesterified -- metabolism
- Inflammation
- Insulin Resistance
- MAP Kinase Kinase 4 -- metabolism
- Macrophages -- metabolism
- Male
- Mice
- Mice, Inbred C57BL
- Models, Biological
- Signal Transduction
- Toll-Like Receptor 2 -- metabolism
- Toll-Like Receptor 4 -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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