A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways.

Nguyen, M T Audrey

A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways. [electronic resource] - The Journal of biological chemistry Nov 2007 - 35279-92 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

0021-9258

10.1074/jbc.M706762200 doi


Adipose Tissue--metabolism
Animals
Bone Marrow Cells--metabolism
CD11b Antigen--biosynthesis
CD11c Antigen--biosynthesis
Fatty Acids, Nonesterified--metabolism
Inflammation
Insulin Resistance
MAP Kinase Kinase 4--metabolism
Macrophages--metabolism
Male
Mice
Mice, Inbred C57BL
Models, Biological
Signal Transduction
Toll-Like Receptor 2--metabolism
Toll-Like Receptor 4--metabolism