A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration. [electronic resource]
Producer: 20071128Description: 16227-32 p. digitalISSN:- 0027-8424
- Aged
- Amino Acid Sequence
- Animals
- Base Sequence
- Chromosomes, Human, Pair 10 -- genetics
- Conserved Sequence
- Gene Expression
- Genetic Predisposition to Disease
- Genetic Variation
- Heterozygote
- High-Temperature Requirement A Serine Peptidase 1
- Homozygote
- Humans
- Linkage Disequilibrium
- Macular Degeneration -- genetics
- Mitochondrial Proteins -- genetics
- Molecular Sequence Data
- Pan troglodytes -- genetics
- Polymorphism, Single Nucleotide
- Proteins -- genetics
- RNA, Messenger -- genetics
- Retina -- metabolism
- Sequence Homology, Amino Acid
- Sequence Homology, Nucleic Acid
- Serine Endopeptidases -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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