A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration.
Kanda, Atsuhiro
A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Oct 2007 - 16227-32 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
0027-8424
10.1073/pnas.0703933104 doi
Aged
Amino Acid Sequence
Animals
Base Sequence
Chromosomes, Human, Pair 10--genetics
Conserved Sequence
Gene Expression
Genetic Predisposition to Disease
Genetic Variation
Heterozygote
High-Temperature Requirement A Serine Peptidase 1
Homozygote
Humans
Linkage Disequilibrium
Macular Degeneration--genetics
Mitochondrial Proteins--genetics
Molecular Sequence Data
Pan troglodytes--genetics
Polymorphism, Single Nucleotide
Proteins--genetics
RNA, Messenger--genetics
Retina--metabolism
Sequence Homology, Amino Acid
Sequence Homology, Nucleic Acid
Serine Endopeptidases--genetics
A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Oct 2007 - 16227-32 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
0027-8424
10.1073/pnas.0703933104 doi
Aged
Amino Acid Sequence
Animals
Base Sequence
Chromosomes, Human, Pair 10--genetics
Conserved Sequence
Gene Expression
Genetic Predisposition to Disease
Genetic Variation
Heterozygote
High-Temperature Requirement A Serine Peptidase 1
Homozygote
Humans
Linkage Disequilibrium
Macular Degeneration--genetics
Mitochondrial Proteins--genetics
Molecular Sequence Data
Pan troglodytes--genetics
Polymorphism, Single Nucleotide
Proteins--genetics
RNA, Messenger--genetics
Retina--metabolism
Sequence Homology, Amino Acid
Sequence Homology, Nucleic Acid
Serine Endopeptidases--genetics