Smn depletion alters profilin II expression and leads to upregulation of the RhoA/ROCK pathway and defects in neuronal integrity. [electronic resource]
Producer: 20071206Description: 120-31 p. digitalISSN:- 0895-8696
- Adrenal Gland Neoplasms -- genetics
- Animals
- Cell Differentiation
- Cyclic AMP Response Element-Binding Protein -- deficiency
- Gene Expression Regulation, Neoplastic
- Immunoblotting
- Nerve Tissue Proteins -- deficiency
- Neurons -- pathology
- PC12 Cells
- Pheochromocytoma -- genetics
- Profilins -- genetics
- Protein Isoforms -- genetics
- RNA-Binding Proteins -- genetics
- Rats
- Reverse Transcriptase Polymerase Chain Reaction
- SMN Complex Proteins
- Survival of Motor Neuron 1 Protein
- rho-Associated Kinases -- genetics
- rhoA GTP-Binding Protein -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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