Smn depletion alters profilin II expression and leads to upregulation of the RhoA/ROCK pathway and defects in neuronal integrity.
Bowerman, Mélissa
Smn depletion alters profilin II expression and leads to upregulation of the RhoA/ROCK pathway and defects in neuronal integrity. [electronic resource] - Journal of molecular neuroscience : MN 2007 - 120-31 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0895-8696
10.1007/s12031-007-0024-5 doi
Adrenal Gland Neoplasms--genetics
Animals
Cell Differentiation
Cyclic AMP Response Element-Binding Protein--deficiency
Gene Expression Regulation, Neoplastic
Immunoblotting
Nerve Tissue Proteins--deficiency
Neurons--pathology
PC12 Cells
Pheochromocytoma--genetics
Profilins--genetics
Protein Isoforms--genetics
RNA-Binding Proteins--genetics
Rats
Reverse Transcriptase Polymerase Chain Reaction
SMN Complex Proteins
Survival of Motor Neuron 1 Protein
rho-Associated Kinases--genetics
rhoA GTP-Binding Protein--genetics
Smn depletion alters profilin II expression and leads to upregulation of the RhoA/ROCK pathway and defects in neuronal integrity. [electronic resource] - Journal of molecular neuroscience : MN 2007 - 120-31 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0895-8696
10.1007/s12031-007-0024-5 doi
Adrenal Gland Neoplasms--genetics
Animals
Cell Differentiation
Cyclic AMP Response Element-Binding Protein--deficiency
Gene Expression Regulation, Neoplastic
Immunoblotting
Nerve Tissue Proteins--deficiency
Neurons--pathology
PC12 Cells
Pheochromocytoma--genetics
Profilins--genetics
Protein Isoforms--genetics
RNA-Binding Proteins--genetics
Rats
Reverse Transcriptase Polymerase Chain Reaction
SMN Complex Proteins
Survival of Motor Neuron 1 Protein
rho-Associated Kinases--genetics
rhoA GTP-Binding Protein--genetics