Lead contamination results in late and slowly repairable DNA double-strand breaks and impacts upon the ATM-dependent signaling pathways. [electronic resource]
Producer: 20071101Description: 201-14 p. digitalISSN:- 0378-4274
- Ataxia Telangiectasia Mutated Proteins
- Cell Cycle Proteins -- metabolism
- Cell Line
- DNA Breaks, Double-Stranded
- DNA Repair -- drug effects
- DNA-Activated Protein Kinase -- metabolism
- DNA-Binding Proteins -- metabolism
- Dose-Response Relationship, Drug
- Endothelial Cells -- drug effects
- G2 Phase -- drug effects
- Histones -- metabolism
- Humans
- Lead -- toxicity
- MRE11 Homologue Protein
- Mutagens -- toxicity
- Nitrates -- toxicity
- Oxidative Stress -- drug effects
- Protein Serine-Threonine Kinases -- metabolism
- Rad51 Recombinase -- metabolism
- Recombination, Genetic -- drug effects
- S Phase -- drug effects
- Signal Transduction -- drug effects
- Time Factors
- Tumor Suppressor Proteins -- metabolism
- X-Rays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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