Ex vivo occupancy of gamma-secretase inhibitors correlates with brain beta-amyloid peptide reduction in Tg2576 mice. [electronic resource]
Producer: 20071105Description: 102-8 p. digitalISSN:- 0022-3565
- Amyloid Precursor Protein Secretases -- antagonists & inhibitors
- Amyloid beta-Protein Precursor -- biosynthesis
- Animals
- Binding Sites
- Brain -- drug effects
- Dose-Response Relationship, Drug
- Enzyme Inhibitors -- chemistry
- Ligands
- Mice
- Mice, Transgenic
- Molecular Structure
- Radioligand Assay
- Time Factors
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Publication Type: Journal Article
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