Expression of CFTR from a ciliated cell-specific promoter is ineffective at correcting nasal potential difference in CF mice. [electronic resource]
Producer: 20071210Description: 1492-501 p. digitalISSN:- 0969-7128
- Amiloride -- pharmacology
- Animals
- Chloride Channels -- metabolism
- Cilia -- physiology
- Cystic Fibrosis -- metabolism
- Cystic Fibrosis Transmembrane Conductance Regulator -- analysis
- Epithelial Cells -- physiology
- Gene Expression
- Genetic Therapy -- methods
- Humans
- Immunoprecipitation
- Membrane Potentials
- Mice
- Mice, Knockout
- Mice, Transgenic
- Nasal Mucosa -- physiology
- Promoter Regions, Genetic
- Reverse Transcriptase Polymerase Chain Reaction
- Sodium Channel Blockers -- pharmacology
- Trachea -- physiology
- Transgenes
- Treatment Failure
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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