Expression of CFTR from a ciliated cell-specific promoter is ineffective at correcting nasal potential difference in CF mice.
Ostrowski, L E
Expression of CFTR from a ciliated cell-specific promoter is ineffective at correcting nasal potential difference in CF mice. [electronic resource] - Gene therapy Oct 2007 - 1492-501 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
0969-7128
10.1038/sj.gt.3302994 doi
Amiloride--pharmacology
Animals
Chloride Channels--metabolism
Cilia--physiology
Cystic Fibrosis--metabolism
Cystic Fibrosis Transmembrane Conductance Regulator--analysis
Epithelial Cells--physiology
Gene Expression
Genetic Therapy--methods
Humans
Immunoprecipitation
Membrane Potentials
Mice
Mice, Knockout
Mice, Transgenic
Nasal Mucosa--physiology
Promoter Regions, Genetic
Reverse Transcriptase Polymerase Chain Reaction
Sodium Channel Blockers--pharmacology
Trachea--physiology
Transgenes
Treatment Failure
Expression of CFTR from a ciliated cell-specific promoter is ineffective at correcting nasal potential difference in CF mice. [electronic resource] - Gene therapy Oct 2007 - 1492-501 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
0969-7128
10.1038/sj.gt.3302994 doi
Amiloride--pharmacology
Animals
Chloride Channels--metabolism
Cilia--physiology
Cystic Fibrosis--metabolism
Cystic Fibrosis Transmembrane Conductance Regulator--analysis
Epithelial Cells--physiology
Gene Expression
Genetic Therapy--methods
Humans
Immunoprecipitation
Membrane Potentials
Mice
Mice, Knockout
Mice, Transgenic
Nasal Mucosa--physiology
Promoter Regions, Genetic
Reverse Transcriptase Polymerase Chain Reaction
Sodium Channel Blockers--pharmacology
Trachea--physiology
Transgenes
Treatment Failure