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  2. Details for: Novel vanilloid receptor-1 antagonists: 2. Structure-activity relationships of 4-oxopyrimidines leading to the selection of a clinical candidate.
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Novel vanilloid receptor-1 antagonists: 2. Structure-activity relationships of 4-oxopyrimidines leading to the selection of a clinical candidate. [electronic resource]

By:
  • Doherty, Elizabeth M
Contributor(s):
  • Fotsch, Christopher
  • Bannon, Anthony W
  • Bo, Yunxin
  • Chen, Ning
  • Dominguez, Celia
  • Falsey, James
  • Gavva, Narender R
  • Katon, Jodie
  • Nixey, Thomas
  • Ognyanov, Vassil I
  • Pettus, Liping
  • Rzasa, Robert M
  • Stec, Markian
  • Surapaneni, Sekhar
  • Tamir, Rami
  • Zhu, Jiawang
  • Treanor, James J S
  • Norman, Mark H
Producer: 20071015Description: 3515-27 p. digitalISSN:
  • 0022-2623
Subject(s):
  • Analgesics -- chemical synthesis
  • Animals
  • Benzothiazoles -- chemical synthesis
  • CHO Cells
  • Calcium -- metabolism
  • Cricetinae
  • Cricetulus
  • Dogs
  • Drug Stability
  • Haplorhini
  • Humans
  • Hyperalgesia -- drug therapy
  • In Vitro Techniques
  • Inflammation -- drug therapy
  • Male
  • Microsomes, Liver -- metabolism
  • Pain Measurement
  • Pyrimidines -- chemical synthesis
  • Rats
  • Rats, Sprague-Dawley
  • Solubility
  • Structure-Activity Relationship
  • TRPV Cation Channels -- antagonists & inhibitors
Online resources:
  • Available from publisher's website
In: Journal of medicinal chemistry vol. 50
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Publication Type: Journal Article

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Novel vanilloid receptor-1 antagonists: 2. Structure-activity relationships of 4-oxopyrimidines leading to the selection of a clinical candidate.

APA

Doherty E. M., Fotsch C., Bannon A. W., Bo Y., Chen N., Dominguez C., Falsey J., Gavva N. R., Katon J., Nixey T., Ognyanov V. I., Pettus L., Rzasa R. M., Stec M., Surapaneni S., Tamir R., Zhu J., Treanor J. J. S. & Norman M. H. (20071015). Novel vanilloid receptor-1 antagonists: 2. Structure-activity relationships of 4-oxopyrimidines leading to the selection of a clinical candidate. : Journal of medicinal chemistry.

Chicago

Doherty Elizabeth M, Fotsch Christopher, Bannon Anthony W, Bo Yunxin, Chen Ning, Dominguez Celia, Falsey James, Gavva Narender R, Katon Jodie, Nixey Thomas, Ognyanov Vassil I, Pettus Liping, Rzasa Robert M, Stec Markian, Surapaneni Sekhar, Tamir Rami, Zhu Jiawang, Treanor James J S and Norman Mark H. 20071015. Novel vanilloid receptor-1 antagonists: 2. Structure-activity relationships of 4-oxopyrimidines leading to the selection of a clinical candidate. : Journal of medicinal chemistry.

Harvard

Doherty E. M., Fotsch C., Bannon A. W., Bo Y., Chen N., Dominguez C., Falsey J., Gavva N. R., Katon J., Nixey T., Ognyanov V. I., Pettus L., Rzasa R. M., Stec M., Surapaneni S., Tamir R., Zhu J., Treanor J. J. S. and Norman M. H. (20071015). Novel vanilloid receptor-1 antagonists: 2. Structure-activity relationships of 4-oxopyrimidines leading to the selection of a clinical candidate. : Journal of medicinal chemistry.

MLA

Doherty Elizabeth M, Fotsch Christopher, Bannon Anthony W, Bo Yunxin, Chen Ning, Dominguez Celia, Falsey James, Gavva Narender R, Katon Jodie, Nixey Thomas, Ognyanov Vassil I, Pettus Liping, Rzasa Robert M, Stec Markian, Surapaneni Sekhar, Tamir Rami, Zhu Jiawang, Treanor James J S and Norman Mark H. Novel vanilloid receptor-1 antagonists: 2. Structure-activity relationships of 4-oxopyrimidines leading to the selection of a clinical candidate. : Journal of medicinal chemistry. 20071015.

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