Novel vanilloid receptor-1 antagonists: 2. Structure-activity relationships of 4-oxopyrimidines leading to the selection of a clinical candidate. (Record no. 17123054)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02162 a2200685 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250515072753.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 200710s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 0022-2623 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1021/jm070190p |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Doherty, Elizabeth M |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20071015 |
| 245 00 - TITLE STATEMENT | |
| Title | Novel vanilloid receptor-1 antagonists: 2. Structure-activity relationships of 4-oxopyrimidines leading to the selection of a clinical candidate. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Journal of medicinal chemistry |
| Date of publication, distribution, etc. | Jul 2007 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 3515-27 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Analgesics |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Benzothiazoles |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | CHO Cells |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Calcium |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cricetinae |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cricetulus |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Dogs |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Stability |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Haplorhini |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Hyperalgesia |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | In Vitro Techniques |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Inflammation |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Male |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Microsomes, Liver |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pain Measurement |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pyrimidines |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rats |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rats, Sprague-Dawley |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Solubility |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Structure-Activity Relationship |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | TRPV Cation Channels |
| General subdivision | antagonists & inhibitors |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Fotsch, Christopher |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bannon, Anthony W |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bo, Yunxin |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chen, Ning |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dominguez, Celia |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Falsey, James |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gavva, Narender R |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Katon, Jodie |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nixey, Thomas |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ognyanov, Vassil I |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pettus, Liping |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rzasa, Robert M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Stec, Markian |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Surapaneni, Sekhar |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tamir, Rami |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zhu, Jiawang |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Treanor, James J S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Norman, Mark H |
| 773 0# - HOST ITEM ENTRY | |
| Title | Journal of medicinal chemistry |
| Related parts | vol. 50 |
| -- | no. 15 |
| -- | p. 3515-27 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1021/jm070190p">https://doi.org/10.1021/jm070190p</a> |
| Public note | Available from publisher's website |
No items available.