Hypoxia-inducible factor 1alpha is regulated by the mammalian target of rapamycin (mTOR) via an mTOR signaling motif. [electronic resource]
Producer: 20070913Description: 20534-43 p. digitalISSN:- 0021-9258
- Amino Acid Motifs -- genetics
- Animals
- Antibiotics, Antineoplastic -- pharmacology
- Cell Hypoxia -- drug effects
- Cell Line, Tumor
- Guanine Nucleotides -- metabolism
- Humans
- Hypoxia-Inducible Factor 1, alpha Subunit -- genetics
- Mice
- Monomeric GTP-Binding Proteins -- genetics
- Mutation, Missense
- Neoplasms -- drug therapy
- Neovascularization, Pathologic -- drug therapy
- Neuropeptides -- genetics
- Protein Binding -- drug effects
- Protein Kinases -- genetics
- Protein Structure, Tertiary -- drug effects
- Ras Homolog Enriched in Brain Protein
- Signal Transduction -- drug effects
- Sirolimus -- pharmacology
- TOR Serine-Threonine Kinases
- Tuberous Sclerosis Complex 2 Protein
- Tumor Suppressor Proteins -- genetics
- Vascular Endothelial Growth Factor A -- genetics
- Von Hippel-Lindau Tumor Suppressor Protein -- genetics
- p300-CBP Transcription Factors -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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