The P2Y2 nucleotide receptor requires interaction with alpha v integrins to access and activate G12. [electronic resource]
Producer: 20071002Description: 1654-62 p. digitalISSN:- 0021-9533
- Amides -- pharmacology
- Antibodies, Monoclonal -- immunology
- Cardiac Myosins -- metabolism
- Cell Line, Tumor
- Cell Movement -- drug effects
- Cofilin 1 -- metabolism
- Enzyme Inhibitors -- pharmacology
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- GTP-Binding Protein alpha Subunits, G12-G13 -- genetics
- GTP-Binding Protein alpha Subunits, Gq-G11 -- metabolism
- Guanosine 5'-O-(3-Thiotriphosphate) -- metabolism
- Humans
- Integrin alphaV -- genetics
- Integrins -- immunology
- Mutation
- Myosin Light Chains -- metabolism
- Oligonucleotides, Antisense -- genetics
- Pertussis Toxin -- pharmacology
- Phosphorylation -- drug effects
- Protein Binding
- Pyridines -- pharmacology
- Receptors, Purinergic P2 -- genetics
- Receptors, Purinergic P2Y2
- Receptors, Vitronectin -- immunology
- Signal Transduction -- genetics
- Stress Fibers -- metabolism
- Transfection
- Uridine Triphosphate -- pharmacology
- rho GTP-Binding Proteins -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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