The P2Y2 nucleotide receptor requires interaction with alpha v integrins to access and activate G12.

Liao, Zhongji

The P2Y2 nucleotide receptor requires interaction with alpha v integrins to access and activate G12. [electronic resource] - Journal of cell science May 2007 - 1654-62 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

0021-9533

10.1242/jcs.03441 doi


Amides--pharmacology
Antibodies, Monoclonal--immunology
Cardiac Myosins--metabolism
Cell Line, Tumor
Cell Movement--drug effects
Cofilin 1--metabolism
Enzyme Inhibitors--pharmacology
Extracellular Signal-Regulated MAP Kinases--metabolism
GTP-Binding Protein alpha Subunits, G12-G13--genetics
GTP-Binding Protein alpha Subunits, Gq-G11--metabolism
Guanosine 5'-O-(3-Thiotriphosphate)--metabolism
Humans
Integrin alphaV--genetics
Integrins--immunology
Mutation
Myosin Light Chains--metabolism
Oligonucleotides, Antisense--genetics
Pertussis Toxin--pharmacology
Phosphorylation--drug effects
Protein Binding
Pyridines--pharmacology
Receptors, Purinergic P2--genetics
Receptors, Purinergic P2Y2
Receptors, Vitronectin--immunology
Signal Transduction--genetics
Stress Fibers--metabolism
Transfection
Uridine Triphosphate--pharmacology
rho GTP-Binding Proteins--metabolism