Dose-dependent inhibition of proteasome activity by a mutant ubiquitin associated with neurodegenerative disease. [electronic resource]
Producer: 20071002Description: 1615-23 p. digitalISSN:- 0021-9533
- Animals
- Blotting, Western
- Cerebral Cortex -- drug effects
- Cysteine Proteinase Inhibitors -- pharmacology
- Cytosol -- metabolism
- Dose-Response Relationship, Drug
- Doxorubicin -- pharmacology
- Flow Cytometry
- Frameshift Mutation
- Gene Expression -- drug effects
- Green Fluorescent Proteins -- genetics
- HeLa Cells
- Humans
- Leupeptins -- pharmacology
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Models, Biological
- Neurodegenerative Diseases -- genetics
- Oligopeptides -- pharmacology
- Proteasome Endopeptidase Complex -- metabolism
- Proteasome Inhibitors
- Tissue Culture Techniques
- Transfection
- Ubiquitin -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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