Dose-dependent inhibition of proteasome activity by a mutant ubiquitin associated with neurodegenerative disease.
van Tijn, Paula
Dose-dependent inhibition of proteasome activity by a mutant ubiquitin associated with neurodegenerative disease. [electronic resource] - Journal of cell science May 2007 - 1615-23 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0021-9533
10.1242/jcs.03438 doi
Animals
Blotting, Western
Cerebral Cortex--drug effects
Cysteine Proteinase Inhibitors--pharmacology
Cytosol--metabolism
Dose-Response Relationship, Drug
Doxorubicin--pharmacology
Flow Cytometry
Frameshift Mutation
Gene Expression--drug effects
Green Fluorescent Proteins--genetics
HeLa Cells
Humans
Leupeptins--pharmacology
Mice
Mice, Inbred C57BL
Mice, Transgenic
Models, Biological
Neurodegenerative Diseases--genetics
Oligopeptides--pharmacology
Proteasome Endopeptidase Complex--metabolism
Proteasome Inhibitors
Tissue Culture Techniques
Transfection
Ubiquitin--genetics
Dose-dependent inhibition of proteasome activity by a mutant ubiquitin associated with neurodegenerative disease. [electronic resource] - Journal of cell science May 2007 - 1615-23 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0021-9533
10.1242/jcs.03438 doi
Animals
Blotting, Western
Cerebral Cortex--drug effects
Cysteine Proteinase Inhibitors--pharmacology
Cytosol--metabolism
Dose-Response Relationship, Drug
Doxorubicin--pharmacology
Flow Cytometry
Frameshift Mutation
Gene Expression--drug effects
Green Fluorescent Proteins--genetics
HeLa Cells
Humans
Leupeptins--pharmacology
Mice
Mice, Inbred C57BL
Mice, Transgenic
Models, Biological
Neurodegenerative Diseases--genetics
Oligopeptides--pharmacology
Proteasome Endopeptidase Complex--metabolism
Proteasome Inhibitors
Tissue Culture Techniques
Transfection
Ubiquitin--genetics