A novel dual-target steroid sulfatase inhibitor and antiestrogen: SR 16157, a promising agent for the therapy of breast cancer. [electronic resource]
Producer: 20080304Description: 191-203 p. digitalISSN:- 0167-6806
- Binding, Competitive
- Blotting, Western
- Breast Neoplasms -- drug therapy
- Cell Proliferation -- drug effects
- Drug Resistance, Neoplasm
- Enzyme Inhibitors -- pharmacology
- Estradiol -- analogs & derivatives
- Estrogen Receptor Modulators -- chemistry
- Fulvestrant
- Humans
- Ligands
- Norpregnatrienes -- chemistry
- Receptors, Estrogen -- metabolism
- Reverse Transcriptase Polymerase Chain Reaction
- Selective Estrogen Receptor Modulators -- pharmacology
- Steryl-Sulfatase -- antagonists & inhibitors
- Tamoxifen -- pharmacology
- Tumor Cells, Cultured -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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