A novel dual-target steroid sulfatase inhibitor and antiestrogen: SR 16157, a promising agent for the therapy of breast cancer.
Rasmussen, Louise M
A novel dual-target steroid sulfatase inhibitor and antiestrogen: SR 16157, a promising agent for the therapy of breast cancer. [electronic resource] - Breast cancer research and treatment Dec 2007 - 191-203 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0167-6806
10.1007/s10549-007-9494-y doi
Binding, Competitive
Blotting, Western
Breast Neoplasms--drug therapy
Cell Proliferation--drug effects
Drug Resistance, Neoplasm
Enzyme Inhibitors--pharmacology
Estradiol--analogs & derivatives
Estrogen Receptor Modulators--chemistry
Fulvestrant
Humans
Ligands
Norpregnatrienes--chemistry
Receptors, Estrogen--metabolism
Reverse Transcriptase Polymerase Chain Reaction
Selective Estrogen Receptor Modulators--pharmacology
Steryl-Sulfatase--antagonists & inhibitors
Tamoxifen--pharmacology
Tumor Cells, Cultured--drug effects
A novel dual-target steroid sulfatase inhibitor and antiestrogen: SR 16157, a promising agent for the therapy of breast cancer. [electronic resource] - Breast cancer research and treatment Dec 2007 - 191-203 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0167-6806
10.1007/s10549-007-9494-y doi
Binding, Competitive
Blotting, Western
Breast Neoplasms--drug therapy
Cell Proliferation--drug effects
Drug Resistance, Neoplasm
Enzyme Inhibitors--pharmacology
Estradiol--analogs & derivatives
Estrogen Receptor Modulators--chemistry
Fulvestrant
Humans
Ligands
Norpregnatrienes--chemistry
Receptors, Estrogen--metabolism
Reverse Transcriptase Polymerase Chain Reaction
Selective Estrogen Receptor Modulators--pharmacology
Steryl-Sulfatase--antagonists & inhibitors
Tamoxifen--pharmacology
Tumor Cells, Cultured--drug effects