5-HT acts on nociceptive primary afferents through an indirect mechanism to induce hyperalgesia in the subcutaneous tissue. [electronic resource]
Producer: 20070626Description: 708-14 p. digitalISSN:- 0306-4522
- Adrenergic beta-2 Receptor Agonists
- Adrenergic beta-2 Receptor Antagonists
- Adrenergic beta-Antagonists -- pharmacology
- Afferent Pathways -- drug effects
- Animals
- Chemotaxis, Leukocyte -- drug effects
- Cyclooxygenase Inhibitors -- pharmacology
- Dose-Response Relationship, Drug
- Hyperalgesia -- chemically induced
- Male
- Nociceptors -- drug effects
- Norepinephrine -- metabolism
- Pain Measurement -- drug effects
- Pain Threshold -- drug effects
- Prostaglandins -- metabolism
- Rats
- Rats, Wistar
- Receptors, Adrenergic, beta-2 -- metabolism
- Receptors, Serotonin, 5-HT3 -- metabolism
- Selectins -- drug effects
- Sensory Receptor Cells -- drug effects
- Serotonin -- metabolism
- Serotonin 5-HT3 Receptor Antagonists
- Serotonin Antagonists -- pharmacology
- Skin -- innervation
- Sympathetic Fibers, Postganglionic -- drug effects
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Publication Type: Journal Article
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