effect of OATP1B transporter inhibition on the pharmacokinetics of atorvastatin in healthy volunteers. [electronic resource]
Producer: 20070423Description: 194-204 p. digitalISSN:- 0009-9236
- Administration, Oral
- Adolescent
- Adult
- Area Under Curve
- Atorvastatin
- Bile -- chemistry
- Binding, Competitive
- Biological Transport -- drug effects
- Cell Line
- Cross-Over Studies
- Enzyme Inhibitors -- administration & dosage
- Female
- Heptanoic Acids -- administration & dosage
- Humans
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- administration & dosage
- Infusions, Intravenous
- Liver -- drug effects
- Liver-Specific Organic Anion Transporter 1
- Male
- Middle Aged
- Organic Anion Transporters -- antagonists & inhibitors
- Pyrroles -- administration & dosage
- Rifampin -- administration & dosage
- Substrate Specificity
- Tablets
- Transfection
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Publication Type: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural
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