Inhibition of histone deacetylase enhances the anti-proliferative action of antiestrogens on breast cancer cells and blocks tamoxifen-induced proliferation of uterine cells. [electronic resource]
Producer: 20080109Description: 297-309 p. digitalISSN:- 0167-6806
- Aromatase -- metabolism
- Breast Neoplasms -- metabolism
- Cell Line
- Cell Proliferation -- drug effects
- Enzyme Inhibitors -- pharmacology
- Estrogen Antagonists -- pharmacology
- Estrogen Receptor alpha -- genetics
- Estrogens -- metabolism
- Female
- Gene Expression Regulation, Neoplastic
- Histone Deacetylase Inhibitors
- Histone Deacetylases -- metabolism
- Humans
- Receptor, ErbB-2 -- metabolism
- Sensitivity and Specificity
- Tamoxifen -- antagonists & inhibitors
- Uterus -- cytology
- Valproic Acid -- pharmacology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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