Inhibition of histone deacetylase enhances the anti-proliferative action of antiestrogens on breast cancer cells and blocks tamoxifen-induced proliferation of uterine cells.
Hodges-Gallagher, Leslie
Inhibition of histone deacetylase enhances the anti-proliferative action of antiestrogens on breast cancer cells and blocks tamoxifen-induced proliferation of uterine cells. [electronic resource] - Breast cancer research and treatment Nov 2007 - 297-309 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
0167-6806
10.1007/s10549-006-9459-6 doi
Aromatase--metabolism
Breast Neoplasms--metabolism
Cell Line
Cell Proliferation--drug effects
Enzyme Inhibitors--pharmacology
Estrogen Antagonists--pharmacology
Estrogen Receptor alpha--genetics
Estrogens--metabolism
Female
Gene Expression Regulation, Neoplastic
Histone Deacetylase Inhibitors
Histone Deacetylases--metabolism
Humans
Receptor, ErbB-2--metabolism
Sensitivity and Specificity
Tamoxifen--antagonists & inhibitors
Uterus--cytology
Valproic Acid--pharmacology
Inhibition of histone deacetylase enhances the anti-proliferative action of antiestrogens on breast cancer cells and blocks tamoxifen-induced proliferation of uterine cells. [electronic resource] - Breast cancer research and treatment Nov 2007 - 297-309 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
0167-6806
10.1007/s10549-006-9459-6 doi
Aromatase--metabolism
Breast Neoplasms--metabolism
Cell Line
Cell Proliferation--drug effects
Enzyme Inhibitors--pharmacology
Estrogen Antagonists--pharmacology
Estrogen Receptor alpha--genetics
Estrogens--metabolism
Female
Gene Expression Regulation, Neoplastic
Histone Deacetylase Inhibitors
Histone Deacetylases--metabolism
Humans
Receptor, ErbB-2--metabolism
Sensitivity and Specificity
Tamoxifen--antagonists & inhibitors
Uterus--cytology
Valproic Acid--pharmacology