Proteasome inhibition induces glutathione synthesis and protects cells from oxidative stress: relevance to Parkinson disease. [electronic resource]
Producer: 20070326Description: 4364-4372 p. digitalISSN:- 0021-9258
- Acetylcysteine -- analogs & derivatives
- Active Transport, Cell Nucleus -- drug effects
- Adrenergic Agents -- toxicity
- Animals
- Cell Nucleus -- metabolism
- Cysteine Proteinase Inhibitors -- pharmacology
- Dose-Response Relationship, Drug
- Glutathione -- biosynthesis
- Hydrogen Peroxide -- toxicity
- Imidazoles -- pharmacology
- Models, Biological
- NF-E2 Transcription Factor -- metabolism
- Oxidants -- toxicity
- Oxidative Stress -- drug effects
- Oxidopamine -- toxicity
- PC12 Cells
- Parkinson Disease -- metabolism
- Proteasome Endopeptidase Complex -- metabolism
- Proteasome Inhibitors
- Pyridines -- pharmacology
- Rats
- Reactive Oxygen Species -- metabolism
- Ubiquitin -- metabolism
- p38 Mitogen-Activated Protein Kinases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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