AICAR potentiates ROS production induced by chronic high glucose: roles of AMPK in pancreatic beta-cell apoptosis. [electronic resource]
Producer: 20070418Description: 791-805 p. digitalISSN:- 0898-6568
- AMP-Activated Protein Kinases
- Aminoimidazole Carboxamide -- analogs & derivatives
- Animals
- Apoptosis -- drug effects
- Cell Line, Transformed
- Down-Regulation -- drug effects
- Enzyme Activation -- drug effects
- Gene Expression -- drug effects
- Glucokinase -- genetics
- Glucose -- pharmacology
- Insulin-Secreting Cells -- cytology
- Membrane Potential, Mitochondrial -- drug effects
- Mice
- Multienzyme Complexes -- metabolism
- Protein Serine-Threonine Kinases -- metabolism
- Proteins -- metabolism
- Rats
- Reactive Oxygen Species -- metabolism
- Ribonucleotides -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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