Allosteric activation of the protein kinase PDK1 with low molecular weight compounds. [electronic resource]
Producer: 20070126Description: 5469-80 p. digitalISSN:- 0261-4189
- 3-Phosphoinositide-Dependent Protein Kinases
- Acetates -- chemistry
- Allosteric Regulation
- Amino Acid Motifs
- Binding Sites
- Cells, Cultured
- Drug Design
- Enzyme Activation
- Humans
- Hydrophobic and Hydrophilic Interactions
- Molecular Weight
- Mutation
- Phosphopeptides -- pharmacology
- Phosphorylation
- Protein Conformation
- Protein Serine-Threonine Kinases -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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