Allosteric activation of the protein kinase PDK1 with low molecular weight compounds.

Engel, Matthias

Allosteric activation of the protein kinase PDK1 with low molecular weight compounds. [electronic resource] - The EMBO journal Nov 2006 - 5469-80 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0261-4189

10.1038/sj.emboj.7601416 doi


3-Phosphoinositide-Dependent Protein Kinases
Acetates--chemistry
Allosteric Regulation
Amino Acid Motifs
Binding Sites
Cells, Cultured
Drug Design
Enzyme Activation
Humans
Hydrophobic and Hydrophilic Interactions
Molecular Weight
Mutation
Phosphopeptides--pharmacology
Phosphorylation
Protein Conformation
Protein Serine-Threonine Kinases--chemistry