Synthetic cryptolepine inhibits DNA binding of NF-kappaB. [electronic resource]
Producer: 20070220Description: 43-9 p. digitalISSN:- 0968-0896
- Alkaloids -- chemical synthesis
- Animals
- Anti-Inflammatory Agents -- chemical synthesis
- Binding Sites
- Binding, Competitive -- drug effects
- Cell Line
- Cells, Cultured
- Cryptolepis -- chemistry
- DNA -- drug effects
- Dose-Response Relationship, Drug
- Drug Evaluation, Preclinical
- Humans
- Indole Alkaloids
- Indoles -- chemical synthesis
- Lipopolysaccharides -- antagonists & inhibitors
- Macrophages -- cytology
- Mice
- NF-kappa B -- antagonists & inhibitors
- Nitric Oxide -- antagonists & inhibitors
- Quinolines -- chemical synthesis
- Structure-Activity Relationship
- Transcription, Genetic -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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