Inhibition of steroid sulfatase activity and cell proliferation in ZR-75-1 and BT-474 human breast cancer cells by KW-2581 in vitro and in vivo. [electronic resource]
Producer: 20071127Description: 211-9 p. digitalISSN:- 0167-6806
- Animals
- Breast Neoplasms -- drug therapy
- Cell Proliferation -- drug effects
- Coumarins -- pharmacology
- Enzyme Inhibitors -- chemical synthesis
- Estradiol -- analogs & derivatives
- Female
- Gene Expression Regulation, Enzymologic -- drug effects
- Humans
- In Vitro Techniques
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Molecular Structure
- Receptors, Progesterone -- metabolism
- Signal Transduction -- drug effects
- Steryl-Sulfatase -- antagonists & inhibitors
- Sulfonamides -- chemical synthesis
- Sulfonic Acids
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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