Inhibition of steroid sulfatase activity and cell proliferation in ZR-75-1 and BT-474 human breast cancer cells by KW-2581 in vitro and in vivo.

Ishida, Hiroyuki

Inhibition of steroid sulfatase activity and cell proliferation in ZR-75-1 and BT-474 human breast cancer cells by KW-2581 in vitro and in vivo. [electronic resource] - Breast cancer research and treatment Aug 2007 - 211-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0167-6806

10.1007/s10549-006-9404-8 doi


Animals
Breast Neoplasms--drug therapy
Cell Proliferation--drug effects
Coumarins--pharmacology
Enzyme Inhibitors--chemical synthesis
Estradiol--analogs & derivatives
Female
Gene Expression Regulation, Enzymologic--drug effects
Humans
In Vitro Techniques
Mice
Mice, Inbred BALB C
Mice, Nude
Molecular Structure
Receptors, Progesterone--metabolism
Signal Transduction--drug effects
Steryl-Sulfatase--antagonists & inhibitors
Sulfonamides--chemical synthesis
Sulfonic Acids
Tumor Cells, Cultured