FLT3 K663Q is a novel AML-associated oncogenic kinase: Determination of biochemical properties and sensitivity to Sunitinib (SU11248). [electronic resource]
Producer: 20061205Description: 2008-14 p. digitalISSN:- 0887-6924
- Acute Disease
- Amino Acid Sequence
- Amino Acid Substitution
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Base Sequence
- Cell Division -- drug effects
- Cell Line, Tumor
- Humans
- Indoles -- pharmacology
- Leukemia, Myeloid -- drug therapy
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Mutagenesis, Site-Directed
- Neoplasm Transplantation
- Point Mutation
- Pyrroles -- pharmacology
- Sunitinib
- fms-Like Tyrosine Kinase 3 -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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