Impact of EGFR point mutations on the sensitivity to gefitinib: insights from comparative structural analyses and molecular dynamics simulations. [electronic resource]
Producer: 20061220Description: 331-46 p. digitalISSN:- 1097-0134
- Adenosine Triphosphate -- chemistry
- Binding Sites
- Computational Biology
- Computer Simulation
- Crystallography, X-Ray
- ErbB Receptors -- chemistry
- Gefitinib
- Ligands
- Models, Molecular
- Point Mutation -- genetics
- Protein Structure, Secondary
- Protein Structure, Tertiary
- Proto-Oncogene Proteins c-abl -- chemistry
- Quinazolines -- chemistry
- Static Electricity
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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