Circulating interleukin-6 induces fever through a STAT3-linked activation of COX-2 in the brain. [electronic resource]
Producer: 20061129Description: R1316-26 p. digitalISSN:- 0363-6119
- Animals
- Body Temperature -- drug effects
- Brain -- metabolism
- Cyclooxygenase 2 -- genetics
- Endothelial Cells -- metabolism
- Fever -- physiopathology
- Gene Expression Regulation -- physiology
- Immune Sera -- immunology
- Interleukin-6 -- blood
- Lipopolysaccharides -- adverse effects
- Male
- NF-kappa B -- genetics
- Pyrogens -- blood
- RNA, Messenger -- genetics
- Rats
- Rats, Sprague-Dawley
- STAT3 Transcription Factor -- genetics
- Suppressor of Cytokine Signaling 3 Protein
- Suppressor of Cytokine Signaling Proteins -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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