JAK1 N-terminus binds to conserved Box 1 and Box 2 motifs of cytokine receptor common beta subunit but signal activation requires JAK1 C-terminus. [electronic resource]
Producer: 20061213Description: 1078-84 p. digitalISSN:- 0730-2312
- Amino Acid Motifs
- Animals
- Conserved Sequence
- Cross-Linking Reagents
- Cytokine Receptor Common beta Subunit -- chemistry
- Humans
- Interleukin-3 Receptor alpha Subunit -- metabolism
- Janus Kinase 1 -- chemistry
- Janus Kinase 2 -- metabolism
- Mice
- Protein Binding
- Protein Structure, Tertiary
- Signal Transduction
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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