The antifibrogenic effect of (-)-epigallocatechin gallate results from the induction of de novo synthesis of glutathione in passaged rat hepatic stellate cells. [electronic resource]
Producer: 20060823Description: 697-709 p. digitalISSN:- 0023-6837
- Animals
- Antioxidants -- pharmacology
- Catechin -- analogs & derivatives
- Cell Culture Techniques
- Cells, Cultured
- Connective Tissue Growth Factor
- Culture Media -- analysis
- Dose-Response Relationship, Drug
- Extracellular Matrix -- drug effects
- Fibrinogen -- antagonists & inhibitors
- Fibrosis -- prevention & control
- Glutathione -- analysis
- Hepatocytes -- cytology
- Immediate-Early Proteins -- pharmacology
- Intercellular Signaling Peptides and Proteins -- pharmacology
- Lipid Peroxidation -- drug effects
- Liver -- cytology
- Male
- Procollagen -- metabolism
- Rats
- Rats, Sprague-Dawley
- Reactive Oxygen Species -- analysis
- Receptors, Transforming Growth Factor beta -- genetics
- Signal Transduction -- drug effects
- Tea
- Transforming Growth Factor beta -- analysis
- Transforming Growth Factor beta1
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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