The antifibrogenic effect of (-)-epigallocatechin gallate results from the induction of de novo synthesis of glutathione in passaged rat hepatic stellate cells.
Yumei, Fu
The antifibrogenic effect of (-)-epigallocatechin gallate results from the induction of de novo synthesis of glutathione in passaged rat hepatic stellate cells. [electronic resource] - Laboratory investigation; a journal of technical methods and pathology Jul 2006 - 697-709 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
0023-6837
10.1038/labinvest.3700425 doi
Animals
Antioxidants--pharmacology
Catechin--analogs & derivatives
Cell Culture Techniques
Cells, Cultured
Connective Tissue Growth Factor
Culture Media--analysis
Dose-Response Relationship, Drug
Extracellular Matrix--drug effects
Fibrinogen--antagonists & inhibitors
Fibrosis--prevention & control
Glutathione--analysis
Hepatocytes--cytology
Immediate-Early Proteins--pharmacology
Intercellular Signaling Peptides and Proteins--pharmacology
Lipid Peroxidation--drug effects
Liver--cytology
Male
Procollagen--metabolism
Rats
Rats, Sprague-Dawley
Reactive Oxygen Species--analysis
Receptors, Transforming Growth Factor beta--genetics
Signal Transduction--drug effects
Tea
Transforming Growth Factor beta--analysis
Transforming Growth Factor beta1
The antifibrogenic effect of (-)-epigallocatechin gallate results from the induction of de novo synthesis of glutathione in passaged rat hepatic stellate cells. [electronic resource] - Laboratory investigation; a journal of technical methods and pathology Jul 2006 - 697-709 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
0023-6837
10.1038/labinvest.3700425 doi
Animals
Antioxidants--pharmacology
Catechin--analogs & derivatives
Cell Culture Techniques
Cells, Cultured
Connective Tissue Growth Factor
Culture Media--analysis
Dose-Response Relationship, Drug
Extracellular Matrix--drug effects
Fibrinogen--antagonists & inhibitors
Fibrosis--prevention & control
Glutathione--analysis
Hepatocytes--cytology
Immediate-Early Proteins--pharmacology
Intercellular Signaling Peptides and Proteins--pharmacology
Lipid Peroxidation--drug effects
Liver--cytology
Male
Procollagen--metabolism
Rats
Rats, Sprague-Dawley
Reactive Oxygen Species--analysis
Receptors, Transforming Growth Factor beta--genetics
Signal Transduction--drug effects
Tea
Transforming Growth Factor beta--analysis
Transforming Growth Factor beta1