IMP dehydrogenase inhibitor mycophenolate mofetil induces caspase-dependent apoptosis and cell cycle inhibition in multiple myeloma cells. [electronic resource]
Producer: 20060504Description: 457-66 p. digitalISSN:- 1535-7163
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Caspases -- metabolism
- Cell Cycle -- drug effects
- Cell Line, Tumor
- Cyclin-Dependent Kinase Inhibitor p21 -- metabolism
- Guanosine -- pharmacology
- Humans
- IMP Dehydrogenase -- antagonists & inhibitors
- Multiple Myeloma -- enzymology
- Mycophenolic Acid -- analogs & derivatives
- Phosphorylation -- drug effects
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- STAT3 Transcription Factor -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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