Mechanisms of antiplatelet activity of PC-09, a newly synthesized pyridazinone derivative. [electronic resource]
Producer: 20060602Description: 32-7 p. digitalISSN:- 0014-2999
- 1-Methyl-3-isobutylxanthine -- pharmacology
- 3',5'-Cyclic-AMP Phosphodiesterases -- antagonists & inhibitors
- Adenosine Triphosphate -- metabolism
- Alprostadil -- pharmacology
- Animals
- Arachidonic Acid -- pharmacology
- Blood Platelets -- drug effects
- Calcium -- metabolism
- Collagen -- pharmacology
- Cyclic AMP -- metabolism
- Cyclic GMP -- metabolism
- Dose-Response Relationship, Drug
- Imidazoles -- pharmacology
- Indomethacin -- pharmacology
- Naphthalenes -- chemistry
- Phosphodiesterase Inhibitors -- pharmacology
- Platelet Aggregation -- drug effects
- Platelet Aggregation Inhibitors -- pharmacology
- Platelet Glycoprotein GPIIb-IIIa Complex -- biosynthesis
- Pyridazines -- chemistry
- Rabbits
- Thrombin -- pharmacology
- Thromboxane A2 -- biosynthesis
- Thromboxane-A Synthase -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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